Immunomodulatory Therapies of Curcumin on Induced Dermatitis

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Ameer Abdul Hussein Abdul AL-Abbas, Shatha Mousa Mlaghee

Abstract

          The aim of this study was to Evaluating the therapeutics and immunomodulatory effect of the curcumin on induced dermatitis, Comparison of therapeutic efficacy between different concertation of curcumin on induced atopic dermatitis in female Albino rats, pure acetone 99.9% in female rats, this study has been carried out at the department of physiology and pharmacology, faculty of veterinary medicine, University of Kufa, Iraq, The study was performed from September to December by evaluating hematological analysis, IL-4, IL33,  histopathology, and. This research was conducted in the animal house, Faculty of Science at the University of Kufa in Iraq, thirty 12-weeks old female Albino rats weighing (150-200g) were supplied from Veterinary Medicine Laboratories (College of Veterinary Medicine, University of Takrit). Rats were placed in plastic cages (six rats per cage) with woods shared for bedding. kept in well-ventilated under controlled temperature (between 23 ºC and 25 C), animals were fed with commercial food from the manufacturer green world company. Rats were assigned randomly one weeks before the experimental period for adaptation.

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