The Use of Bioluminescent Beetles in Biomedical Research and Drug Discovery

Abstract

Bioluminescent beetles, such as the common firefly, have been utilized for their unique biological properties in biomedical research and drug discovery for several decades. The ability of these insects to emit light through a chemical reaction has allowed researchers to develop sensitive assays for various biological processes, such as gene expression, protein-protein interactions, and enzyme activity. This paper presents a comprehensive review of the current understanding of the use of bioluminescent beetles in biomedical research and drug discovery, including their chemistry, biology, and applications in various fields.